Coagulation Factor VIIIa

《英文msh詞典》Coagulation Factor VIIIa
[同義詞] Coagulation Factor VIIIa
[主題詞] Factor VIIIa
[中文釋義] 凝血因子Ⅷa
[英文釋義] Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similiar in structure and generation to factor Va.

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